PowerTOST - Power and Sample Size for (Bio)Equivalence Studies
Contains functions to calculate power and sample size for various study designs used in bioequivalence studies. Use known.designs() to see the designs supported. Power and sample size can be obtained based on different methods, amongst them prominently the TOST procedure (two one-sided t-tests). See README and NEWS for further information.
Last updated 11 months ago
9.61 score 20 stars 4 dependents 112 scripts 1.4k downloadsPower2Stage - Power and Sample-Size Distribution of 2-Stage Bioequivalence Studies
Contains functions to obtain the operational characteristics of bioequivalence studies in Two-Stage Designs (TSD) via simulations.
Last updated 1 years ago
3.11 score 1 stars 13 scripts 358 downloadsrandomizeBE - Create a Random List for Crossover Studies
Contains a function to randomize subjects, patients in groups of sequences (treatment sequences). If a blocksize is given, the randomization will be done within blocks. The randomization may be controlled by a Wald-Wolfowitz runs test. Functions to obtain the p-value of that test are included. The package is mainly intended for randomization of bioequivalence studies but may be used also for other clinical crossover studies. Contains two helper functions sequences() and williams() to get the sequences of commonly used designs in BE studies.
Last updated 2 years ago
1.30 score 1 stars 6 scripts 233 downloads